Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia refers to autosomal recessive diseases that result from gene mutation. CAH is a genetic disorder that causes the adrenal glands to secrete excessive amounts of androgen during prenatal development.

Baby girls suffering with CAH are more masculinized, can have enlarged clitorises that resemble penises, may prefer masculine activities and engaging with male playmates to a greater extent than girls without these large amounts of androgen.

Symptoms vary with the type of CAH and gender. Due to the excess androgens, symptoms include ambiguous genitalia (mostly in females), rapid growth during childhood, early pubic hair, excessive facial hair, menstrual irregularity and infertility.